Helminths turning on the NLRP3 inflammasome: Pros and cons

Celias, Daiana Pamela; Motran, Claudia Cristina; Cervi, Laura Alejandra

info:eu-repo/semantics/article

Fecha

2020-02

Registro en:

Celias, Daiana Pamela; Motran, Claudia Cristina; Cervi, Laura Alejandra; Helminths turning on the NLRP3 inflammasome: Pros and cons; Elsevier; Trends In Parasitology; 36; 2; 2-2020; 87-90

1471-4922

http://hdl.handle.net/11336/129390

CONICET Digital

CONICET

https://repositorioslatinoamericanos.uchile.cl/handle/2250/4365263

Autor

Celias, Daiana Pamela

Motran, Claudia Cristina

Cervi, Laura Alejandra

Institución

Consejo Nacional de Investigaciones Científicas y Tecnológicas (Argentina)

Resumen

Helminth infections can activate multimeric protein complexes called inflammasomes. In this forum we summarize the main effects of the NLRP3 inflammasome activation, including control of excessive Th2 response and immunopathology induction. These mechanisms would ensure the survival of both the host and the parasite.

Materias

HELMINTHS

IMMUNOPATHOLOGY

INFLAMMASOME ACTIVATION

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