info:eu-repo/semantics/article
A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation
Fecha
2018-07Registro en:
Achkar, Natalia Patricia; Cho, Seok Keun; Poulsen, Christian; Arce, Agustín Lucas; Ré, Delfina Adela; et al.; A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation; Cell Press; Developmental Cell; 46; 2; 7-2018; 236-247
1534-5807
CONICET Digital
CONICET
Autor
Achkar, Natalia Patricia
Cho, Seok Keun
Poulsen, Christian
Arce, Agustín Lucas
Ré, Delfina Adela
Giudicatti, Axel Joel
Karayekov, Elizabeth Irene
Ryu, Moon Young
Choi, Suk Won
Harholt, Jesper
Casal, Jorge José
Yang, Seong Wook
Manavella, Pablo Andrés
Resumen
Achkar et al. show that a nuclear reserve pool of inactive phosphorylated HYL1, an essential cofactor for microRNA biogenesis, is resistant to dark- or shade-induced degradation. Upon light restoration, this HYL1 pool is quickly dephosphorylated to rapidly restore miRNA production and switch the developmental program to light-dependent growth.