info:eu-repo/semantics/article
TPRV-1 expression in human preeclamptic placenta
Fecha
2016-04Registro en:
Martinez, Nora Alicia; Aban, Cyntia Estefania; Leguizamon, Gustavo Federico; Damiano, Alicia Ermelinda; Farina, Mariana; TPRV-1 expression in human preeclamptic placenta; W B Saunders Co Ltd; Placenta; 40; 4-2016; 25-28
0143-4004
CONICET Digital
CONICET
Autor
Martinez, Nora Alicia
Aban, Cyntia Estefania
Leguizamon, Gustavo Federico
Damiano, Alicia Ermelinda
Farina, Mariana
Resumen
Preeclampsia is a multisystem disorder unique to human pregnancy, characterized by abnormal placentation. Although its causes remain unclear, it is known that the expression of several transporters is altered. Transient receptor potential vanilloid 1 (TRPV-1) is a nonselective cation channel, present in human placenta. Here, we evaluated the expression of TRPV-1 in preeclamptic placentas. We observed a deregulation in TRPV-1 expression in these placentas which may explain the impaired Ca2+ homeostasis found in preeclampsia.