info:eu-repo/semantics/article
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Fecha
2018-01-23Registro en:
Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A.; Abrams, John M.; Adam, Dieter; et al.; Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018; Nature Publishing Group; Cell Death and Differentiation; 25; 3; 23-1-2018; 486-541
1350-9047
CONICET Digital
CONICET
Autor
Galluzzi, Lorenzo
Vitale, Ilio
Aaronson, Stuart A.
Abrams, John M.
Adam, Dieter
Agostinis, Patrizia
Alnemri, Emad S.
Altucci, Lucia
Amelio, Ivano
Andrews, David W.
Annicchiarico Petruzzelli, Margherita
Antonov, Alexey V.
Arama, Eli
Baehrecke, Eric H.
Barlev, Nickolai A.
Bazan, Nicolas G.
Bernassola, Francesca
Bertrand, Mathieu J. M.
Bianchi, Katiuscia
Blagosklonny, Mikhail V.
Blomgren, Klas
Borner, Christoph
Boya, Patricia
Brenner, Catherine
Campanella, Anibal
Candi, Eleonora
Carmona Gutierrez, Didac
Cecconi, Francesco
Chan, Francis K. M.
Chandel, Navdeep S.
Cheng, Emily H.
Chipuk, Jerry E.
Cidlowski, John A.
Ciechanover, Aaron
Cohen, Gerald M.
Conrad, Marcus
Cubillos Ruiz, Juan R.
Czabotar, Peter E.
D´Angiolella, Vincenzo
Dawson, Ted M.
Dawson, Valina L.
De Laurenzi, Vincenzo
De Maria, Ruggero
Debatin, Klaus Michael
De Berardinis, Ralph J.
Deshmukh, Mohanish
Di Daniele, Nicola
Di Virgilio, Francesco
Dixit, Vishva M.
Dixon, Scott J.
Duckett, Colin S.
Dynlacht, Brian D.
El Deiry, Wafik S.
Elrod, John W.
Fimia, Gian Maria
Fulda, Simone
García Sáez, Ana J.
Garg, Abhishek D.
Garrido, Carmen
Gavathiotis, Evripidis
Golstein, Pierre
Gottlieb, Eyal
Green, Douglas R.
Greene, Lloyd A.
Gronemeyer, Hinrich
Gross, Atan
Hajnoczky, Gyorgy
Hardwick, J. Marie
Harris, Isaac S.
Hengartner, Michael O.
Hetz, Claudio
Ichijo, Hidenori
Jäättelä, Marja
Joseph, Bertrand
Jost, Philipp J.
Juin, Philippe P.
Kaiser, William J.
Karin, Michael
Kaufmann, Thomas
Kepp, Oliver
Kimchi, Adi
Kitsis, Richard N.
Klionsky, Daniel J.
Knight, Richard A.
Kumar, Sharad
Lee, Sam W.
Lemasters, John J.
Levine, Beth
Linkermann, Andreas
Lipton, Stuart A.
Lockshin, Richard A.
López Otín, Carlos
Lowe, Scott W.
Luedde, Tom
Lugli, Enrico
MacFarlane, Marion
Madeo, Frank
Malewicz, Michal
Malorni, Walter
Manic, Gwenola
Marine, Jean-Christophe
Martin, Seamus J.
Martinou, Jean Claude
Medema, Jan Paul
Mehlen, Patrick
Meier, Pascal
Melino, Sonia
Miao, Edward A.
Molkentin, Jeffery D.
Moll, Ute M.
Muñoz Pinedo, Cristina
Nagata, Shigekazu
Nuñez, Gabriel
Oberst, Andrew
Oren, Moshe
Overholtzer, Michael
Pagano, Michele
Panaretakis, Theocharis
Pasparakis, Manolis
Penninger, Josef M.
Pereira, David M.
Pervaiz, Shazib
Peter, Marcus E.
Piacentini, Mauro
Pinton, Paolo
Prehn, Jochen H.M.
Puthalakath, Hamsa
Rabinovich, Gabriel Adrián
Rehm, Markus
Rizzuto, Rosario
Rodrigues, Cecilia M.P.
Rubinsztein, David C.
Rudel, Thomas
Ryan, Kevin M.
Sayan, Emre
Scorrano, Luca
Shao, Feng
Shi, Yufang
Silke, John
Simon, Hans Uwe
Sistigu, Antonella
Stockwell, Brent R.
Strasser, Andreas
Szabadkai, Gyorgy
Tait, Stephen W.G.
Tang, Daolin
Tavernarakis, Nektarios
Thorburn, Andrew
Tsujimoto, Yoshihide
Turk, Boris
Vanden Berghe, Tom
Vandenabeele, Peter
Vander Heiden, Matthew G.
Villunger, Andreas
Virgin, Herbert W.
Vousden, Karen H.
Vucic, Domagoj
Wagner, Erwin F.
Walczak, Henning
Wallach, David
Wang, Ying
Wells, James A.
Wood, Will
Yuan, Junying
Zakeri, Zahra
Zhivotovsky, Boris
Zitvogel, Laurence
Melino, Gerry
Kroemer, Guido
Resumen
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field.