info:eu-repo/semantics/article
Lipase-catalyzed synthesis and characterization of a novel linear polyamidoamine oligomer
Fecha
2010-03Registro en:
Monsalve, Leandro Nicolas; Kaniz Fatema, M.; Nonami, Hiroshi; Erra Balsells, Rosa; Baldessari, Alicia; Lipase-catalyzed synthesis and characterization of a novel linear polyamidoamine oligomer; Elsevier; Polymer; 51; 14; 3-2010; 2998-3005
0032-3861
CONICET Digital
CONICET
Autor
Monsalve, Leandro Nicolas
Kaniz Fatema, M.
Nonami, Hiroshi
Erra Balsells, Rosa
Baldessari, Alicia
Resumen
A linear polyamidoamine oligomer was obtained by polymerization of ethyl acrylate and N-methyl-1,3-diaminopropane, catalyzed by the Candida antarctica lipase. Depending on the reaction conditions such as substrates concentration, solvent and enzyme:substrate ratio, the enzyme catalyzes the polymerization reaction or Michael adducts formation. The polymeric material, characterized by FTIR, 1H and 13C NMR and UV-MALDI-TOF-MS, shows low molecular weight and high monodispersity. The activity showed by C. antarctica lipase in the polymerization reaction is highly selective and allows to obtain a product with potential biomedical applications in mild condition reactions and low environmental impact.