info:eu-repo/semantics/article
Permethylated β-cyclodextrin in liquid poly(oxyethylene) as a stationary phase for capillary gas chromatography
Fecha
2009-10Registro en:
Osorio Grisales, Jaiver; Lebed, Pablo Jorge; Keunchkarian, Sonia; González, Francisco R.; Castells, Cecilia Beatriz Marta; Permethylated β-cyclodextrin in liquid poly(oxyethylene) as a stationary phase for capillary gas chromatography; Elsevier Science; Journal of Chromatography - A; 1216; 40; 10-2009; 6844-6851
0021-9673
CONICET Digital
CONICET
Autor
Osorio Grisales, Jaiver
Lebed, Pablo Jorge
Keunchkarian, Sonia
González, Francisco R.
Castells, Cecilia Beatriz Marta
Resumen
This paper reports the study of poly(oxyethylene) as a solvent for heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin (PM-β-CD) and the potential of these mixtures for constructing enantioselective gas chromatography columns. Enantioseparations of volatile racemic mixtures using capillaries coated with 10–50% PM-β-CD diluted in Carbowax 20M were evaluated. The influence of the polymer type on retention, separation and reproducibility over a period of time is critically discussed. The poly(oxyethylene)-based columns were also compared to columns prepared by dilution of PM-β-CD in two polysiloxanes, SE-30 and SE-54, at several temperatures. Finally, we evaluated a new stationary phase prepared by crosslinking the chiral selector to the poly(oxyethylene) matrix.