info:eu-repo/semantics/article
Entorno genético de CTX-M-2 en aislamientos de Klebsiella pneumoniae provenientes de pacientes hospitalizados en Uruguay
Fecha
2006-12Registro en:
Vignoli, R.; Cordeiro, N.; Seija, V.; Schelotto, F.; Radice, Marcela Alejandra; et al.; Entorno genético de CTX-M-2 en aislamientos de Klebsiella pneumoniae provenientes de pacientes hospitalizados en Uruguay; Asociación Argentina de Microbiología; Revista Argentina de Microbiología; 38; 12-2006; 84-88
0325-7541
1851-7617
CONICET Digital
CONICET
Autor
Vignoli, R.
Cordeiro, N.
Seija, V.
Schelotto, F.
Radice, Marcela Alejandra
Ayala, J.
Power, Pablo
Gutkind, Gabriel Osvaldo
Resumen
We studied two CTX-M-2-producing Klebsiella pneumoniae clinical strains, K96005 and K13, isolated from hospitalized patients in Uruguay, during 1996 and 2003, respectively. The genomic surroundings of bla(CTX-M-2) were characterized by PCR-mapping and DNA sequencing. Our results show that blaCTX-M-2 is included in a complex class-1 integron (InK13), associated with an orf513 in both isolates. The genetic array of the integron, aac(6´)-lb, bla(OxA,2), orfD (gene cassette region), associated with an orf513-bla(CTX-M-2), seems to be widely disseminated over the Rio de la Plata region.