dc.creatorHaruna, Noriko
dc.creatorAcosta, Delicia Ester
dc.creatorNakagawa, Satoshi
dc.creatorKohei, Yamaguchi
dc.creatorAkira, Tai
dc.creatorOkuyama, Tadashi
dc.creatorTakashi, Suguimura
dc.date.accessioned2019-05-21T14:59:02Z
dc.date.accessioned2022-10-15T03:12:40Z
dc.date.available2019-05-21T14:59:02Z
dc.date.available2022-10-15T03:12:40Z
dc.date.created2019-05-21T14:59:02Z
dc.date.issued2004-12
dc.identifierHaruna, Noriko; Acosta, Delicia Ester; Nakagawa, Satoshi; Kohei, Yamaguchi; Akira, Tai; et al.; Asymmetric Hydrogenation of Furan- containing Ketones over Tartaric Acid-modified Raney Nickel Catalyst; Pergamon-Elsevier Science Ltd; Heterocycles; 62; 1; 12-2004; 375-386
dc.identifierhttp://hdl.handle.net/11336/76786
dc.identifier1881-0942
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4338739
dc.description.abstractThe hydrogenation of b-keto esters containing a furan unit at the conjugated position to the b-carbonyl group was carried out over a chiral heterogeneous catalyst, tartaric acid-modified Raney nickel. The hydrogenation first proceeds at the carbonyl to give optically active alcohols, but a simple substrate undergoes further hydrogenation of the furan part to produce a diastereomeric mixture of alcohols having a tetrahydrofuran moiety. This overreduction was efficiently suppressed by substitutions of a substituent at the furan part. The optical yield at the hydroxy group is in the range of 40–90%.
dc.languageeng
dc.publisherPergamon-Elsevier Science Ltd
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3987/COM-03-S(P)17
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectASYMETRIC HYDROGENATION
dc.subjectFURANE
dc.subjectTARTARIC MODIFIED RANEY NICKEL
dc.subjectKETONES
dc.titleAsymmetric Hydrogenation of Furan- containing Ketones over Tartaric Acid-modified Raney Nickel Catalyst
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


Este ítem pertenece a la siguiente institución