info:eu-repo/semantics/article
The human-microbiome superorganism and its modulation to restore health
Fecha
2019-10Registro en:
Salvucci, Emiliano Jesus; The human-microbiome superorganism and its modulation to restore health; Taylor & Francis Ltd; International Journal of Food Sciences and Nutrition; 70; 7; 10-2019; 781-795
0963-7486
1465-3478
CONICET Digital
CONICET
Autor
Salvucci, Emiliano Jesus
Resumen
Microbiome is the community of microorganism that co-live with a host. The human being is the result of the integration of its genome and the coexistence with millions of microorganisms throughout its evolutionary history. Human-microbiome association can be considered a step of integration in evolution, constituting a superorganism. Many emergent diseases are related to the loss of part of this microbiome and its restoration can be achieved by different strategies. Gut microbiome imbalance is particularly associated with numerous inflammatory, immune and nervous system-related diseases by a communication pathway called microbiome–brain axis. Modulation of microbiome by administering prebiotics, like arabinoxylans, and synbiotics is a plausible treatment for dysbiosis, the regulation of neurotransmitters and alleviation of neurological manifestations.