info:eu-repo/semantics/article
Efficient synthesis of chiral Δ2-1,3,4-thiadiazolines from α-pinene and verbenone
Fecha
2011-10Registro en:
Sarmiento, Gabriela Pabla; Rouge, Pablo D.; Fabian, Lucas Emanuel; Vega, Daniel Roberto; Ortuño, Rosa M.; et al.; Efficient synthesis of chiral Δ2-1,3,4-thiadiazolines from α-pinene and verbenone; Pergamon-Elsevier Science Ltd; Tetrahedron: Asymmetry; 22; 10-2011; 1924-1929
0957-4166
CONICET Digital
CONICET
Autor
Sarmiento, Gabriela Pabla
Rouge, Pablo D.
Fabian, Lucas Emanuel
Vega, Daniel Roberto
Ortuño, Rosa M.
Moltrasio, Graciela Yolanda
Moglioni, Albertina Gladys
Resumen
The synthesis of chiral cyclobutane 1,3,4-thiadiazoline derivatives starting from (-)alfa pinene and (-)verbenone was studied. The diastereoisomeric excesses of the products obtained depended strongly upon the starting chiral ketone. The stereochemical assignments of the synthesized compounds were performed by NMR spectroscopy, X-ray analysis, and theoretical calculations.