info:eu-repo/semantics/article
Novel atibacterial resin-based filling material containing nanoparticles for the potential one-step treatment of caries
Fecha
2019-03Registro en:
Angel Villegas, Natalia; Silvero, María Jazmín; Sainz Ajá, Martin; Rocca, Diamela María; Becerra, María Cecilia; et al.; Novel atibacterial resin-based filling material containing nanoparticles for the potential one-step treatment of caries; Hindawi Publishing Corporation; Journal of Healthcare Engineering; 2019; 3-2019; 40454-40463
2040-2295
2040-2309
CONICET Digital
CONICET
Autor
Angel Villegas, Natalia
Silvero, María Jazmín
Sainz Ajá, Martin
Rocca, Diamela María
Becerra, María Cecilia
Molina, Gustavo Fabián
Palma, Santiago Daniel
Resumen
The aim of this work was to study the application of resin filling containing nanomaterials for the potential treatment of caries. Zinc nanoparticles (ZnO@NP, 50 nm) were chosen for their antimicrobial capacity against aerobic bacteria, and here, they have proved to be bactericidal against anaerobic bacterial strains (Streptococcus mutans, Streptococcus mitis, and Lactobacillus spp.). Potential mechanism of action is proposed based on microbiological assays and seems to be independent of oxidative stress because the nanoparticles are effective in microaerophilic conditions. The loading of nanoparticles on the demineralized dental surface and their infiltration power were significantly improved when ZnO@NP were carried by the resin. Overall, this material seems to have a high potential to become a one-step treatment for caries lesions.