info:eu-repo/semantics/article
Fe3O4@Au@mSiO2 as an enhancing nanoplatform for Rose Bengal photodynamic activity
Fecha
2017-08Registro en:
Rosa Pardo, I.; Roig Pons, M.; Heredia, Adrián Alberto; Usagre, J. V.; Ribera, A.; et al.; Fe3O4@Au@mSiO2 as an enhancing nanoplatform for Rose Bengal photodynamic activity; Royal Society of Chemistry; Nanoscale; 9; 29; 8-2017; 10388-10396
2040-3364
2040-3372
CONICET Digital
CONICET
Autor
Rosa Pardo, I.
Roig Pons, M.
Heredia, Adrián Alberto
Usagre, J. V.
Ribera, A.
Galian, Raquel Eugenia
Pérez Prieto, J.
Resumen
A novel nanoplatform composed of three types of materials with different functionalities, specifically core-shell Fe3O4@Au nanoparticles encapsulated near the outer surface of mesoporous silica (mSiO2) nanoparticles, has been successfully synthesised and used to enhance the efficiency of a photosensitiser, namely Rose Bengal, in singlet oxygen generation. Fe3O4 is responsible for the unusual location of the Fe3O4@Au nanoparticle, while the plasmonic shell acts as an optical antenna. In addition, the mesoporous silica matrix firmly encapsulates Rose Bengal by chemical bonding inside the pores, thus guaranteeing its photostability, and in turn making the nanosystem biocompatible. Moreover, the silica surface of the nanoplatform ensures further functionalisation on demand.