info:eu-repo/semantics/article
Turning the table on miRNAs
Fecha
2018-03Registro en:
de la Mata, Manuel; Großhans, Helge; Turning the table on miRNAs; Nature Publishing Group; Nature Structural and Molecular Biology; 25; 3; 3-2018; 195-197
1545-9993
CONICET Digital
CONICET
Autor
de la Mata, Manuel
Großhans, Helge
Resumen
Transcripts with highly complementary sequences can target microRNAs (miRNAs) for degradation, but the physiological relevance of target-directed miRNA degradation (TDMD) has remained unclear. Bitetti et al. now identify a conserved vertebrate RNA that induces TDMD in the cerebellum of zebrafish and mouse to promote wild-type animal behaviors.