Genomic and phylogenetic analysis of hepatitis C virus isolates from Argentine patients: A six-year retrospective study

dc.creatorQuarleri, Jorge Fabian
dc.creatorRobertson, B.H.
dc.creatorMathet, Veronica Lidia
dc.creatorFeld, Mariana
dc.creatorEspínola, Luis Alberto
dc.creatorRequeijo, M.P.
dc.creatorMandó, Oscar Gaspar
dc.creatorCarballal, Guadalupe
dc.creatorOubiña, Jose Raul
dc.date.accessioned2021-04-19T12:06:16Z
dc.date.accessioned2022-10-15T01:05:13Z
dc.date.available2021-04-19T12:06:16Z
dc.date.available2022-10-15T01:05:13Z
dc.date.created2021-04-19T12:06:16Z
dc.date.issued2000-12
dc.identifierQuarleri, Jorge Fabian; Robertson, B.H.; Mathet, Veronica Lidia; Feld, Mariana; Espínola, Luis Alberto; et al.; Genomic and phylogenetic analysis of hepatitis C virus isolates from Argentine patients: A six-year retrospective study; American Society for Microbiology; Journal of Clinical Microbiology; 38; 12; 12-2000; 4560-4568
dc.identifier0095-1137
dc.identifierhttp://hdl.handle.net/11336/130328
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4328033
dc.description.abstractTyping of hepatitis C virus (HCV) isolates from Argentine patients was performed by using different methodologies in a population of 243 patients. HCV subtype was assigned based upon restriction fragment length polymorphism (RFLP). HCV RNA genomes obtained from serum samples were classified as belonging to clade 1 (53.5%), 2 (23.0%), or 3 (8.6%); 14.8% of samples showed HCV mixed infections, more frequently implying different subtypes within the same clade. In addition to RFLP typing, phylogenetic relatedness among sequences from both 5′ untranslated region (n = 50) and nonstructural 5B coding region (n = 15) was established.
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://jcm.asm.org/content/38/12/4560.long
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC87637/
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1128/JCM.38.12.4560-4568.2000
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHepatitis C virus
dc.subjectHCV genotypes
dc.subjectArgentina
dc.subjectPhylogenetic analysis
dc.titleGenomic and phylogenetic analysis of hepatitis C virus isolates from Argentine patients: A six-year retrospective study
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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