info:eu-repo/semantics/article
Delineating the "galectin signature" of the tumor microenvironment
Fecha
2013-04Registro en:
Compagno, Daniel Georges; Laderach, Diego Jose; Gentilini, Lucas Daniel; Jaworski, Felipe Martín; Rabinovich, Gabriel Adrián; Delineating the "galectin signature" of the tumor microenvironment; Landes Bioscience; OncoImmunology; 2; 4; 4-2013; 1-13
2162-4011
2162-402X
CONICET Digital
CONICET
Autor
Compagno, Daniel Georges
Laderach, Diego Jose
Gentilini, Lucas Daniel
Jaworski, Felipe Martín
Rabinovich, Gabriel Adrián
Resumen
Galectins, a family of glycan-binding proteins, can control tumor progression by promoting transformation, angiogenesis and immune escape. We identified a dynamically regulated 'galectin signature', which delineates the progression of prostate cancer, highlighting galectin-1 as an attractive target for anti-angiogenic therapy in advanced stages of the disease.