info:eu-repo/semantics/article
Ontogenetic growth of multicellular tumor spheroids
Fecha
2006-11Registro en:
Condat, Carlos; Menchón, Silvia Adriana; Ontogenetic growth of multicellular tumor spheroids; Elsevier Science; Physica A: Statistical Mechanics and its Applications; 371; 1; 11-2006; 76-79
0378-4371
CONICET Digital
CONICET
Autor
Condat, Carlos
Menchón, Silvia Adriana
Resumen
In ontogenetic growth models, the basal metabolic rate is usually assumed to depend on the individual mass following a power law. Here it is shown that, in the case of multicellular tumor spheroids, the emergence of a necrotic core invalidates this assumption. The implications of this result for spheroid growth are discussed, and a procedure to determine the growth parameters using macroscopic measurements is proposed.