info:eu-repo/semantics/article
Highly Sensitive and selective glucose biosensing at carbon paste electrodes modified with electrogenerated magnetite nanoparticles and glucose oxidase
Fecha
2010-07Registro en:
Comba, Fausto Nahuel; Rubianes, María Dolores; Cabrera, Lourdes; Gutiérrez, Silvia; Herrasti, Pilar; et al.; Highly Sensitive and selective glucose biosensing at carbon paste electrodes modified with electrogenerated magnetite nanoparticles and glucose oxidase; Wiley VCH Verlag; Electroanalysis; 22; 14; 7-2010; 1566-1572
1040-0397
CONICET Digital
CONICET
Autor
Comba, Fausto Nahuel
Rubianes, María Dolores
Cabrera, Lourdes
Gutiérrez, Silvia
Herrasti, Pilar
Rivas, Gustavo Adolfo
Resumen
This work reports the advantages of carbon paste electrodes modified with electrogenerated magnetite nanoparticles. The nanoparticles present catalytic activity towards hydrogen peroxide reduction. The incorporation of glucose oxidase (GOx) and magnetite in a carbon paste matrix have made possible the development of an efficient glucose biosensor. The effect of the amount of GOx and magnetite present in the composite on the response of the biosensor was critically evaluated. The biosensors demonstrated to be highly selective, with negligible interference of ascorbic acid and uric acid. The proposed biosensor was challenged with human blood serum demonstrating an excellent correlation with the spectrophotometric method.