info:eu-repo/semantics/article
Radical Fluoroalkylation Reactions
Fecha
2018-08Registro en:
Barata Vallejo, Sebastian; Cooke, María Victoria; Postigo, A.; Radical Fluoroalkylation Reactions; American Chemical Society; ACS Catalysis; 8; 8; 8-2018; 7287-7307
2155-5435
CONICET Digital
CONICET
Autor
Barata Vallejo, Sebastian
Cooke, María Victoria
Postigo, A.
Resumen
Recent protocols and reactions for catalytic radical perfluoroalkylations will be described. The production of perfluoroalkyl radicals (RF = CnF2n+1, n ≥ 2), which effect both addition and substitution reactions on organic substrates, can be realized through a range of diverse methods such as the well-established visible-light transition-metal-mediated photocatalysis, organic-dye-photocatalyzed reactions, electron donor-acceptor complexes, and more recently frustrated Lewis pairs. Thus, perfluoroalkylation reactions of carbon-carbon multiple bonds, isocyanides, nitrones, hydrazones, β-keto esters, α-cyano arylacetates, sulfides, and (hetero)arenes will be described. Special emphasis will be placed on examples published after 2015, where higher fluorinated series of fluoroalkylating reagents are studied.