info:eu-repo/semantics/article
Expression of Fcγ receptors type II (FcγRII) in chronic lymphocytic leukemia B cells [4]
Fecha
2003-10Registro en:
Gamberale, Romina; Geffner, Jorge Raúl; Sanjurjo, Julieta; Fernandez Calloti, Paula X.; Arrosagaray, Guillermo; et al.; Expression of Fcγ receptors type II (FcγRII) in chronic lymphocytic leukemia B cells [4]; American Society of Hematology; Blood; 102; 7; 10-2003; 2698-2699
0006-4971
CONICET Digital
CONICET
Autor
Gamberale, Romina
Geffner, Jorge Raúl
Sanjurjo, Julieta
Fernandez Calloti, Paula X.
Arrosagaray, Guillermo
Sánchez Ávalos, Julio César Américo
Giordano, Mirta Nilda
Resumen
We have read with interest the paper from Damle et al analyzing the surface membrane phenotype of B lymphocytes in chronic lymphocytic leukemia (B-CLL). The authors stated that the leukemic cells from all B-CLL patients evaluated (irrespective of immunoglobulin heavy chain (IgVH) gene mutational status) bear the phenotype of antigen-experienced B cells based, among other features, on the very low expression of Fcγ receptors type IIb (FcγRIIb, CD32), which is the main isoform of FcγRII in B lymphocytes.