info:eu-repo/semantics/article
Hantavirus Pulmonary Syndrome in Tucumán province associated to an unexpected viral genotype
Fecha
2017-05Registro en:
Ciancaglini, Matías; Bellomo, Carla María; Torres Cabrero Clara; Alonso Daniel ; Bassi, Sabrina Cecilia; et al.; Hantavirus Pulmonary Syndrome in Tucumán province associated to an unexpected viral genotype; Medicina (Buenos Aires); Medicina (Buenos Aires); 77; 5-2017; 81-84
0025-7680
1669-9106
CONICET Digital
CONICET
Autor
Ciancaglini, Matías
Bellomo, Carla María
Torres Cabrero Clara
Alonso Daniel
Bassi, Sabrina Cecilia
Iglesias, Ayelén Aluminé
Martinez, Valeria Paula
Resumen
We describe the characterization of the viral genotype involved in the first case of hantavirus pul-monary syndrome reported in Tucumán, a Northwestern province of Argentina. A 23-year-old woman, with no record of travel history and previously diagnosed with an antiphospholipid syndrome, died after 11 days of severe cardiopulmonary insufficiency. Among the four endemic regions of hantavirus pulmonary syndrome in Argentina, the Northwest Region has the highest incidence, exceeding 50% of all reported cases in the country. Until now, only Salta and Jujuy (2 out of the 6 provinces composing the Northwest Region), reported cases of hantavirus pulmonary syndrome, all of which occurred in the Yungas Forest area. Remarkably, the viral genotype characterized in this case showed higher nucleotide identity with the Andes-BsAs genotype most prevalent in Buenos Aires province, located 1400 km apart from Tucumán, than with any of the commonly found genotypes in the Northwest Region. The Andes-BsAs genotype has been associated with 30% lethality and interhuman transmission in Buenos Aires province. Interhuman transmission cannot be ruled out in the present case.