info:eu-repo/semantics/article
Phytotoxic phenylpropanoids isolated from Ophryosporus charua (Griseb.) Hieron
Fecha
2017-06Registro en:
Bravetti, Margarita María del Milagro; Vico, Raquel Viviana; Carpinella, Maria Cecilia; Ferrayoli, Carlos Guillermo; Palacios, Sara Maria; Phytotoxic phenylpropanoids isolated from Ophryosporus charua (Griseb.) Hieron; Pergamon-Elsevier Science Ltd; Phytochemistry; 138; 6-2017; 145-151
0031-9422
CONICET Digital
CONICET
Autor
Bravetti, Margarita María del Milagro
Vico, Raquel Viviana
Carpinella, Maria Cecilia
Ferrayoli, Carlos Guillermo
Palacios, Sara Maria
Resumen
Bioguided isolation of the EtOH extract from the medicinal native plant, Ophryosporus charua, against Raphanus sativus, yielded three phenylpropanoids, charuol A [(Z)-4-((1S,2R)-3-acetoxy-1,2-dihydroxypropyl)phenyl) 2-methylbut-2-enoate], charuepoxide [(Z)-4-((2S,3R)-3-(acetoxymethyl oxiran-2-yl)phenyl) 2-methylbut-2-enoate] and charuol B [(Z)-4-((1R,2R)-3-acetoxy-1,2-dihydroxypropyl)phenyl) 2-methylbut-2-enoate]. Their structures and absolute configuration were established by extensive spectroscopic analyses. The effective concentrations for 50% inhibition of germination (ECg50) and root (ECr50) and shoot (ECs50) elongations were determined for these compounds against P. miliaceum (monocot) and Raphanus sativus (dicot). Charuol A was the most active in the inhibition of germination of P. miliaceum (ECg50 = 0.97 mM), followed by charuol B and charuepoxide, although charuol B was the most effective in regulating the root growth of P. miliaceum seedlings, with an ECr50 of 1.0 mM. Charuol A inhibited the germination of R. sativus, while its seedling development was also affected by all three compounds with different effectiveness. Charuol A was also highly effective in the 0.09–0.30 mM range against other test species such as Lactuca sativa, Eruca sativa, Allium ampeloprasum and Secale cereale.