info:eu-repo/semantics/article
Adherence of Packing Defects in Soluble Proteins
Fecha
2003-07Registro en:
Fernandez, Ariel; Scott, L. Ridgway; Adherence of Packing Defects in Soluble Proteins; American Physical Society; Physical Review Letters; 91; 1; 7-2003; 18102-18102
0031-9007
1079-7114
CONICET Digital
CONICET
Autor
Fernandez, Ariel
Scott, L. Ridgway
Resumen
For protein structure to prevail in water, its backbone hydrogen bonds must be shielded from water attack, requiring a cluster of “wrapping” nonpolar groups. Thus, underwrapped regions are adhesive, as exogenous removal of surrounding water becomes thermodynamically favorable. Here we measure the average adhesive force exerted by an underwrapped hydrogen bond on a test hydrophobe and thus define a new interactivity constant.