Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts

dc.creatorHan, Shu-Ying
dc.creatorChu, Jin-Xiu
dc.creatorLi, Guang-Min
dc.creatorZhu, Li-Sha
dc.creatorShi, Rui-Fang
dc.date2010
dc.date2010-02-17T03:00:00Z
dc.identifierhttp://sedici.unlp.edu.ar/handle/10915/7883
dc.identifierhttp://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf
dc.descriptionRutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuring the protein synthesis rate through 3H-leucine incorporation, and the MTT method. Rutin (0.8 to 8.0 mg/l) exhibited a strong inhibition on the hypertrophy and proliferation. The results suggested that rutin from buckwheat flowers and leaves might have protective effects on cardiac hypertrophy.
dc.descriptionColegio de Farmacéuticos de la Provincia de Buenos Aires
dc.formatapplication/pdf
dc.format137-140
dc.languageen
dc.relationLatin American Journal of Pharmacy
dc.relationvol. 29, no. 1
dc.subjectFarmacia
dc.titleEffects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
dc.typeArticulo
dc.typeComunicacion


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