Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia

dc.creatorAkhter, Afsana
dc.creatorRahman, Mohammad S.
dc.creatorAhsan, Monira
dc.date2009-06-18T03:00:00Z
dc.date2008
dc.date.accessioned2017-03-08T20:12:19Z
dc.date.available2017-03-08T20:12:19Z
dc.identifierhttp://hdl.handle.net/10915/7713
dc.identifierhttp://www.latamjpharm.org/trabajos/27/6/LAJOP_27_6_2_6_IYD0ZJ2048.pdf
dc.identifierhttp://sedici.unlp.edu.ar/handle/10915/7713
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/429780
dc.descriptionThe plant Jatropha pandurifolia (Euphorbiaceae) has ethnopharmacological reputation of being used as a healing agent in Bangladesh. In this study, preliminary screenings were conducted to look at the antimicrobial susceptibility and cytotoxicity of the plant extract. The n-hexane extract of the plant was subjected to screening for inhibition of microbial growth by the disc diffusion method and the average zone of inhibition was found 12-21 mm at a concentration of 500 μg/disc. The extract was also subjected to brine shrimp lethality bioassay for primary cytotoxicity evaluation and it revealed significant cytotoxicity with LC50 of 4.67 μg/ml. This is the first report of the antimicrobial activity and cytotoxicity of J. pandurifolia.
dc.languageen
dc.relationLatin American Journal of Pharmacy
dc.relationvol. 27, no. 6
dc.subjectantimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia
dc.subjectFarmacia
dc.subjectFarmacología
dc.subjectPlantas medicinales
dc.subjectTest de Citotoxicidad
dc.titlePreliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
dc.typeArtículos de revistas
dc.typeComunicacion


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