Microwave-assisted synthesis of ethyl 7-chloro-4-oxo-l,4-dihydro-1,8- naphthyridine-3-carboxylate by the Grohe-Heitzer reaction

dc.creatorLeyva Ramos, Socorro
dc.creatorLeyva, Elisa
dc.creatorCardoso Ortiz, Jaime
dc.creatorHernández López, Hiram
dc.date.accessioned2021-05-25T22:52:07Z
dc.date.accessioned2022-10-14T15:13:22Z
dc.date.available2021-05-25T22:52:07Z
dc.date.available2022-10-14T15:13:22Z
dc.date.created2021-05-25T22:52:07Z
dc.date.issued2017
dc.identifier1870-249X
dc.identifierhttp://ricaxcan.uaz.edu.mx/jspui/handle/20.500.11845/2510
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4247009
dc.description.abstractA simple and efficient two-step method was implemented for the synthesis of ethyl 7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate. Comparing with the reported Grohe-Heitzer reaction, the time and the reaction steps have been reduced using microwave irradiation. This compound is an important intermediate for the preparation of naphthyridone derivatives which have received significant attention due to their broad spectrum of biological activity.
dc.languagespa
dc.publisherSociedad Química de México
dc.relationhttps://doi.org/10.29356/jmcs.v61i1.127
dc.relationgeneralPublic
dc.relationhttps://www.jmcs.org.mx/index.php/jmcs/article/view/127
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/3.0/us/
dc.rightsAtribución-NoComercial-CompartirIgual 3.0 Estados Unidos de América
dc.sourceJournal of the Mexican Chemical Society, 2017, 61(1), 50-53
dc.titleMicrowave-assisted synthesis of ethyl 7-chloro-4-oxo-l,4-dihydro-1,8- naphthyridine-3-carboxylate by the Grohe-Heitzer reaction
dc.typeArtículos de revistas


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