Artículo de investigación que tiene por objetivo hacer una evaluación nutritiva de bloques multinutricionales elaborados con frutos de Stenocereus griseus y S. stellatus, en sustitución de melaza de caña de azúcarThe present study was carried out in order to evaluate the chemical composition, as well as the digestibility of organic matter and the NDF of multinutritional blocks (BMN) based on pitaya (Stenocereus griseus) and xoconostle (Stenocereus stellatus) in substitution of sugarcane molasses. BMN were made from (Stenocereus griseus L.) and (Stenocereus stellatus) whose composition in both cases was: whole fruit 35%, cement 3.00%, lime, 5.00%, salt 5.00%, urea 5.00%, molasses 15.00,% corn stubble 30.00 %, mineral salt 2%. The blocks made from pitaya (BMNP) had, on a dry basis, a CP percentage of 27.98 ± 0.75, compared to the blocks made with xoconostle (BMNX) (Stenocereus stellatus) 27.58 ± 0.78. The average crude fiber value for BMNP was 15.61 ± 2.61 vs. 15.52 ± 1.365 for BMNX and had no difference at (P> 05). Regarding NDF, the results show values (BMNP) of 36.65% ± 1.50 compared to BMNX 35.63% ± 0.54. With respect to the FAD, the amounts for BMNP 25.04% ± 0.74 and for BMNX 24.32% ± 0.87. The acid detergent lignin values were 5.31 ± 0.91 and 4.96 ± 0.6. In all cases there was no significant difference at (P> 05). The in vitro digestibility by means of the gas production technique showed a digestibility percentage for BMNP of 50.48 ± 3.85 and for BMNX of 57.15 ± 2.75. Tukey's test showed a significant difference at (P <05).no patrocinadores, no financiación