info:eu-repo/semantics/article
Hyphal ontogeny in Neurospora crassa: a model organism for all seasons
Author
MERITXELL RIQUELME PEREZ
Institutions
Abstract
"Filamentous fungi have proven to be a better-suited model system than unicellular yeasts in analyses of cellular processes such as polarized growth, exocytosis, endocytosis, and cytoskeleton-based organelle traffic. For example, the filamentous fungus Neurospora crassa develops a variety of cellular forms. Studying the molecular basis of these forms has led to a better, yet incipient, understanding of polarized growth. Polarity factors as well as Rho GTPases, septins, and a localized delivery of vesicles are the central elements described so far that participate in the shift from isotropic to polarized growth. The growth of the cell wall by apical biosynthesis and remodeling of polysaccharide components is a key process in hyphal morphogenesis. The coordinated action of motor proteins and Rab GTPases mediates the vesicular journey along the hyphae toward the apex, where the exocyst mediates vesicle fusion with the plasma membrane. Cytoplasmic microtubules and actin microfilaments serve as tracks for the transport of vesicular carriers as well as organelles in the tubular cell, contributing to polarization. In addition to exocytosis, endocytosis is required to set and maintain the apical polarity of the cell. Here, we summarize some of the most recent breakthroughs in hyphal morphogenesis and apical growth in N. crassa and the emerging questions that we believe should be addressed."
Related items
Showing items related by title, author, creator and subject.
-
Compendio de innovaciones socioambientales en la frontera sur de México
Adriana Quiroga -
Caminar el cafetal: perspectivas socioambientales del café y su gente
Eduardo Bello Baltazar; Lorena Soto_Pinto; Graciela Huerta_Palacios; Jaime Gomez -
Material de empaque para biofiltración con base en poliuretano modificado con almidón, metodos para la manufactura del mismo y sistema de biofiltración
OLGA BRIGIDA GUTIERREZ ACOSTA; VLADIMIR ALONSO ESCOBAR BARRIOS; SONIA LORENA ARRIAGA GARCIA