Tesis
Treinamento aeróbio de natação aumenta a atividade de enzimas antioxidantes e o conteúdo de glicogênio no músculo esquelético de ratos
Fecha
2013-03-14Registro en:
VIEIRA JUNIOR, Roberto Carlos. Treinamento aeróbio de natação aumenta a atividade de enzimas antioxidantes e o conteúdo de glicogênio no músculo esquelético de ratos. 2013. 62 f. Dissertação (Mestrado em Biociências) - Universidade Federal de Mato Grosso, Faculdade de Nutrição, Cuiabá, 2013.
Autor
Voltarelli, Fabrício Azevedo
http://lattes.cnpq.br/8710187484419682
Voltarelli, Fabrício Azevedo
294.893.518-06
http://lattes.cnpq.br/8710187484419682
Simões, Herbert Gustavo
144.434.748-97
http://lattes.cnpq.br/8009374693903397
294.893.518-06
Fett, Carlos Alexandre
329.119.121-87
http://lattes.cnpq.br/1802404946212461
Institución
Resumen
The present study verified the effects of aerobic swimming training (AST) on
biomarkers of oxidative stress, glycogen content and cell growth in the skeletal
muscle of rats. Eighteen male Wistar rats (60 days) were divided into two groups:
Sedentary Group (GS; n=10): sedentary rats; and Trained Group (GT; n=8): rats
subjected to AST (5.0% of body weight), 1h/day, 5x/week, during 8 weeks. The
activity of antioxidant enzymes (AOE) superoxide dismutase (SOD [U/ml]), catalase
(CAT [µmol/min.mg protein]), glutathione peroxidase (GPx [nmol/min/100mg]), and
substances that react with thiobarbituric acid levels (TBARs [nmol MDA/mg protein])
were determined in the right gastrocnemius muscle. Glycogen (mg/100mg), protein
(g/100g), and DNA (g/100g) contents were evaluated in the left gastrocnemius
muscle. The Mann-Whitney test was used to detect differences between the means.
AOE activity was higher in the GT group (CAT: 0.87±0.04; SOD: 6.49±0.45; GPX:
6.49±0.52) when compared to GS group (CAT: 0.52±0.03; SOD: 4.10±0.37; GPx:
2.87±0.35). TBARs levels was lower in GT (GS: 8.90 ± 0.47; GT: 2.35±0.45;).
Gastrocnemius glycogen content (GS: 0.108±0.013; GT: 0.320±0.012) and
protein/DNA ratio (GS: 24.94±3.25; GT: 41.68±4.02) were higher in GT group.
Altogether, these data provide evidence that AST improved antioxidant defense,
which may be associated with increased glycogen content and cell growth,
hypertrophic level, skeletal muscle of animals.