Detección de ADN de parvovirus B19 en donantes de sangre de tres hospitales en Santiago, Chile

dc.creatorLÉVICAN,JORGE
dc.creatorTORRES,MAURICIO
dc.creatorGAGGERO,NICOLÁS
dc.creatorCORVALÁN,ROSA
dc.creatorGAGGERO,ALDO
dc.date2011-02-01
dc.date.accessioned2017-03-07T16:37:23Z
dc.date.available2017-03-07T16:37:23Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000200001
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/404734
dc.descriptionBackground: Parvovirus B19 (B19) is associated with a wide range of diseases in humans, whose severity depends on the immunological and hematological status of the host. It is transmitted mainly through the airway but also by transfusions. Aim: To determine the B19 DNA carrier frequency in a population of volunteer blood donors from three hospitals blood banks in Santiago, Chile, and to determine the viral load in DNA positive cases. Material and Methods: A total of477 serum samples were analyzed. The screening of B19 DNA was carried out by nested polymerase chain reaction (PCR) directed to the non-structural region of the virus (NS1). The viral load in positives cases was quantified by NS1 Real Time PCR. Results: Parvovirus B19 was detected in four samples, rendering a frequency of 1:119. The viral loads ranged from less than 2000 to 5,626 x 10(5) genome equivalents/ml. Conclusions: Parvovirus B19 was present in four of 477 blood bank blood donors from three hospitals in Santiago.
dc.formattext/html
dc.languagees
dc.publisherSociedad Médica de Santiago
dc.sourceRevista médica de Chile v.139 n.2 2011
dc.subjectBlood banks
dc.subjectGenome, human
dc.subjectParvovirus B19, human
dc.titleDetección de ADN de parvovirus B19 en donantes de sangre de tres hospitales en Santiago, Chile
dc.typeArtículos de revistas


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