SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL EVALUATION OF FEW 2, 3-SUBSTITUTED QUINOXALINES

dc.creatorJAYACHANDRA REDDY,B
dc.creatorSOMASEKHARA REDDY,M.C
dc.date2010-12-01
dc.date.accessioned2017-03-07T16:35:07Z
dc.date.available2017-03-07T16:35:07Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000400016
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/404102
dc.descriptionThe quinoxaline derivatives (i-v) were synthesized through cyclization-oxidation of a- bromo carbonyl compounds with o-phenyl diamines (7a and 10a) and further coupling at 6-position via Suzuki reaction using PdCl2 (dppf).DCM, ter. BuNH2, Na2CO3 in IPA, H2O refluxed for 16 h. As the results of antibacterial screening tests done by paper disc method, quinoxaline derivatives (i) and (v) revealed significant inhibition zone on Bacillus spericus and quinoxaline derivatives (iii) and (v) on Escherichia coli cultures.
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Química
dc.sourceJournal of the Chilean Chemical Society v.55 n.4 2010
dc.subjectQuinoxaline
dc.subjectSuzuki
dc.subjectCoupling
dc.subjectmicrowave
dc.subjectBacillus spericus
dc.subjectEscherichia coli
dc.titleSYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL EVALUATION OF FEW 2, 3-SUBSTITUTED QUINOXALINES
dc.typeArtículos de revistas


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