dc.creatorAwobajo,F. O
dc.creatorRaji,Y
dc.creatorAkinloye,A. K
dc.date2010-12-01
dc.date.accessioned2017-03-07T16:33:42Z
dc.date.available2017-03-07T16:33:42Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400047
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/403689
dc.descriptionStudies on testes and epididymis tissue of rats treated orally for fourteen days with therapeutic doses of cloxacillin (6mg/100g/day), ampicillin (4mg/100/day) and tetracycline (12mg/100g/day) separately showed a significant reduction in testicular and epididimis architecture. Microscopic studies of these male reproductive organs further revealed a significant alteration in the epididymis as revealed by a significant reduction (p<0.05) in epididymal ductular diameter (EDD), and epididymal epithelial height (EEH) in treated group of animals. A significant increase (p<0.05) was however recorded in epididymal luminal diameter (ELD) in all the animals after the two and three week's recovery period allowed. This gives another insight into the toxicity activities of these antibiotics on male reproductive organs, apart from reduction in serum testosterone level, decreased sperm motility, decreased spermatozoa count and decrease in RNA and DNA content of spermatogenic cells as earlier reported.
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Anatomía
dc.sourceInternational Journal of Morphology v.28 n.4 2010
dc.subjectAntibiotics
dc.subjectTestes
dc.subjectEpididymis
dc.subjectHistomorphometry
dc.titleHistomorphometric Changes in the Testes and Epididymis of Wistar Strain Albino Rats Following Fourteen Days Oral Administration of Therapeutic Doses of Some Antibiotics
dc.typeArtículos de revistas


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