Brasil | Artigo
dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorHosp Municipal Dr Munir Rafful
dc.contributorUniv Ctr Volta Redonda
dc.creatorLuderer, Loreley A. [UNIFESP]
dc.creatorLustosa, Suzana A. S. [UNIFESP]
dc.creatorNeto, Ricardo Artigiani [UNIFESP]
dc.creatorLopes, Filipe T.
dc.creatorMatos, Delcio [UNIFESP]
dc.date.accessioned2016-01-24T14:27:33Z
dc.date.accessioned2022-10-07T20:59:03Z
dc.date.available2016-01-24T14:27:33Z
dc.date.available2022-10-07T20:59:03Z
dc.date.created2016-01-24T14:27:33Z
dc.date.issued2012-08-01
dc.identifierInternational Journal of Surgical Pathology. Thousand Oaks: Sage Publications Inc, v. 20, n. 4, p. 355-359, 2012.
dc.identifier1066-8969
dc.identifierhttp://repositorio.unifesp.br/handle/11600/35158
dc.identifier10.1177/1066896912437412
dc.identifierWOS:000306428800004
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4025665
dc.description.abstractObjective. Since the first data from a patient with colorectal adenocarcinoma are obtained by biopsy, this study evaluated the accuracy of diagnosis by biopsy as compared with the diagnostic potential of the surgical specimen, considering the histological type, grade of differentiation, and immunohistochemical expression of p53. Methods. the specimens were obtained from 80 patients assisted at Hospital São Paulo. the biopsy and surgical specimen sections were stained by hematoxylin-eosin and immunohistochemistry and compared by 3 pathologists blinded to the evaluations. Results. the accuracy for the histological types was 88%. the grade of differentiation presented an accuracy of 70% with Kappa = .48. the expression of protein p53 exhibited an accuracy of 68% with Kappa = .22. Conclusion. the preoperative biopsy of colorectal adenocarcinoma presented good accuracy compared with histopathological examination of the surgical specimen, but with weak to moderate effective degree of agreement between the results.
dc.languageeng
dc.publisherSage Publications Inc
dc.relationInternational Journal of Surgical Pathology
dc.rightshttp://www.uk.sagepub.com/aboutus/openaccess.htm
dc.rightsAcesso restrito
dc.subjectcolorectal adenocarcinoma
dc.subjectcolorectal biopsy
dc.subjectsurgical specimen
dc.subjectaccuracy
dc.subjectcolorectal carcinoma
dc.titleAccuracy of Preoperative Biopsies Compared With Surgical Specimens in the Diagnosis of Colorectal Adenocarcinoma
dc.typeArtigo


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