Artigo
Advances in the non-linear optical investigation of lyotropic-like low-density human lipoproteins in the native and oxidised states
Fecha
2014-03-04Registro en:
Liquid Crystals. Abingdon: Taylor & Francis Ltd, v. 41, n. 3, p. 465-470, 2014.
0267-8292
10.1080/02678292.2014.889857
WOS:000333994900018
Autor
Alves, S. [UNIFESP]
Figueiredo Neto, A. M.
Institución
Resumen
The Z-Scan optical technique was recently used to measure the non-linear optical response of human lipoproteins, in particular low-density lipoprotein (LDL) particles, regarding their oxidative (atherogenic) state. the higher is the oxidation degree of the LDL particle, the smaller is their non-linear optical response. the main physical process involved in this phenomenon is the increase in the thermal diffusivity of the aqueous LDL solution, as a function of the oxidation degree. the responsible for the heat diffusion across the sample are the hydroperoxides generated by the oxidation. Other human lipoproteins were shown to present non-linear optical responses in the thermal timescale regime. the non-linear optical response of LDL solutions may be used in the development of new tools to quantify the atherogenic particles in the human blood.