dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorUniversidade de São Paulo (USP)
dc.creatorChaves, Marcelo Donizeti [UNIFESP]
dc.creatorSouza Nunes, Leandro Soeiro de
dc.creatorOliveira, Renato Victor de
dc.creatorHolgado, Leandro Andrade
dc.creatorNary Filho, Hugo
dc.creatorMatsumoto, Mariza Akemi
dc.creatorRibeiro, Daniel Araki [UNIFESP]
dc.date.accessioned2016-01-24T14:28:05Z
dc.date.accessioned2022-10-07T20:44:25Z
dc.date.available2016-01-24T14:28:05Z
dc.date.available2022-10-07T20:44:25Z
dc.date.created2016-01-24T14:28:05Z
dc.date.issued2012-12-01
dc.identifierJournal of Cranio-maxillofacial Surgery. Edinburgh: Churchill Livingstone, v. 40, n. 8, p. E315-E320, 2012.
dc.identifier1010-5182
dc.identifierhttp://repositorio.unifesp.br/handle/11600/35564
dc.identifier10.1016/j.jcms.2012.01.014
dc.identifierWOS:000209175700016
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4022111
dc.description.abstractPurpose: the aim of this study was to analyze and compare the expression of osteocalcin, RANK-L, osteoprotegerin, in sinus lift procedures using bovine hydroxyapatite (HA).Material and methods: Twenty four male rabbits underwent bilateral sinus lift procedures were distributed into two groups, according to the sinus filling material: Group 1) autogenous bone graft; and Group 2) bovine HA. All groups were sacrificed after 14 and 30 days, for microscopic and immunohistochemistry analysis.Results: At 14 days after surgery, discrete osteogenesis was observed in the highly vascularized granulation tissue surrounding HA particles, as well as woven bone deposition on the biomaterial surface. Following 30 days, well organized bone trabeculas were seen surrounding the HA granules presenting areas of osteogenic activity. Morphometric findings did not show remarkable differences between groups. Bovine HA induced similar osteocalcin, RANK-L, osteoprotegerin immunoexpressivity when compared to autogenous bone graft group for both periods evaluated in this setting.Conclusion: Taken together, these data are consistent with the notion that HA has a similar biological behavior to autogenous bone graft in sinus lift of rabbits. (C) 2012 European Association for Cranio-Maxillo-Facial Surgery.
dc.languageeng
dc.publisherChurchill Livingstone
dc.relationJournal of Cranio-maxillofacial Surgery
dc.rightsAcesso restrito
dc.subjectBovine hidroxiapatite
dc.subjectSinus lift
dc.subjecteNOS
dc.subjectOsteocalcin
dc.subjectRANK-L
dc.subjectosteoprotegerin
dc.titleBovine hydroxyapatite (Bio-Oss (R)) induces osteocalcin, RANK-L and osteoprotegerin expression in sinus lift of rabbits
dc.typeArtigo


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