Successful Intra-arterial Thrombolysis in a Patient with an Intracranial Meningioma

dc.contributorHosp Coracao
dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorBaiense, Robson Fantinato [UNIFESP]
dc.creatorAbrahao, Agessandro [UNIFESP]
dc.creatorRicarte, Irapua F. [UNIFESP]
dc.creatorFukuda, Thiago G. [UNIFESP]
dc.creatorOliveira, Ricardo A. [UNIFESP]
dc.creatorSilva, Gisele S. [UNIFESP]
dc.creatorCosta, Maristela
dc.creatorTeixeira, Manoel J.
dc.date.accessioned2016-01-24T14:34:40Z
dc.date.accessioned2022-10-07T20:31:44Z
dc.date.available2016-01-24T14:34:40Z
dc.date.available2022-10-07T20:31:44Z
dc.date.created2016-01-24T14:34:40Z
dc.date.issued2013-11-01
dc.identifierJournal of Stroke & Cerebrovascular Diseases. Amsterdam: Elsevier B.V., v. 22, n. 8, p. E658-E660, 2013.
dc.identifier1052-3057
dc.identifierhttp://repositorio.unifesp.br/handle/11600/36946
dc.identifier10.1016/j.jstrokecerebrovasdis.2013.05.009
dc.identifierWOS:000327719000066
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4019082
dc.description.abstractAlteplase (recombinant tissue plasminogen activator [rt-PA]) label approval by the Food and Drug Administration remarks the contraindication of its use with known intracranial neoplasm because of potential bleeding complications. Despite this concern, the real risk of intracerebral bleeding in patients with intracranial neoplasms treated with rt-PA is unknown, and there are few reports of thrombolysis in patients with brain tumors. We report a case of a 78-year-old man who was seen in our emergency department within 2 hours from sudden onset of aphasia, right-sided hemiplegia, hypoesthesia, and homonymous hemianopsia. the National Institutes of Health Stroke Scale (NIHSS) score at admission was 20. Intra-arterial thrombolysis was performed with administration of .3 mg/kg of alteplase combined with mechanical thrombectomy. At discharge, his NIHSS score was 1, and after 90 days, his modified Rankin score was 1. To our knowledge, this is the first report of intra-arterial thrombolysis in a patient with acute ischemic stroke with an intracranial tumor.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationJournal of Stroke & Cerebrovascular Diseases
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.rightsAcesso restrito
dc.subjectIntra-arterial thrombolysis
dc.subjectmeningioma
dc.subjectintracranial neoplasm
dc.subjectacute ischemic stroke
dc.subjectmechanical thrombectomy
dc.subjectintracranial hemorrhage
dc.titleSuccessful Intra-arterial Thrombolysis in a Patient with an Intracranial Meningioma
dc.typeArtigo


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