Artigo de Periódico
Biological Effect of Leaf Aqueous Extract of Caesalpinia pyramidalis in Goats Naturally Infected with Gastrointestinal Nematodes
Fecha
2012Autor
Santos, Roberto Robson Borges dos
López, Jorge A.
Santos, Luciano Cincurá Silva
Zacharias, Farouk
David, Jorge Mauricio
David, Juceni Pereira de Lima
Lima, Fernanda Washington de Mendonça
Institución
Resumen
Forty-eight goats naturally infected with gastrointestinal nematodes were randomly divided into four groups (n = 12): negative
control (G1) (untreated), positive control (G2) (treated with doramectin, 1mL/50 Kg b.w.), and G3 and G4 treated with 2.5 and
5mg/Kg b.w. of a leaf aqueous extract of Caesalpinia pyramidalis (CP). Fecal and blood samples were regularly collected for the evaluation of fecal egg count (FEC), hematological and immunological parameters to assess the anthelmintic activity. In treated animals with CP, there was noted a significant reduction of 54.6 and 71.2% in the mean FEC (P < 0.05). An increase in IgA
levels was observed in G3 and G4 (P < 0.05), during the experimental period, suggesting that it was stimulated by the extract
administration. In conclusion, the results showed that CP provoked a protective response in infected animals treated with them. This response could be partly explained by the CP chemical composition.