Artigo de Periódico
Long lasting BCG protection against leprosy
Fecha
2007Registro en:
0264-410X
v. 25, n. 39-40
Autor
Rodrigues, Laura Cunha
Kerr, Ligia Regina Franco Sansigolo
Frietas, Max Victor Carioca
Barreto, Mauricio Lima
Rodrigues, Laura Cunha
Kerr, Ligia Regina Franco Sansigolo
Frietas, Max Victor Carioca
Barreto, Mauricio Lima
Institución
Resumen
Background: BCG vaccine protects against leprosy.
Objectives: Estimate BCG protection against leprosy by age by age.
Methods: A case control study with 226 cases of leprosy and 857 controls. BCG vaccination was ascertained via examination of BCG scars. Protection is presented for three age groups.
Results: BCG protection against leprosy was 86% (95% CI: 77–92%) in the age group 18–29; 54% (95% CI: −37% to 85%) in the age group 30–39 and 32% (95% CI: −3% to 56%) in those aged 40 or more.
Conclusions: BCG efficacy against leprosy may well last for three decades and possibly even longer. BCG vaccination must have contributed to worldwide reduction in leprosy incidence.