New Diterpenoids from Leaves of Guarea macrophylla (Meliaceae)

Abstract

The hexane phase from the ethanol extract from leaves of Guarea macrophylla (Meliaceae) was submitted to chromatographic separation. These procedures allowed the isolation of one new diterpenoid: 7a-hydroperoxy-isopimara-8(14),15-diene-2a,3b-diol, one new nor-diterpenoid: 19-nor-isopimara-7,15,4(18)-trien-3-one besides seven known diterpenoids. Their structures were deduced by analysis of spectrometric data and comparison of data described in the literature.