Artigo de Periódico
Métodos simples de formação de monocristal de substância orgânica para estudo estrutural por difração de raios X
Fecha
2008Registro en:
0100-4042
v. 31, n. 4.
Autor
Cunha, Silvio do Desterro
Cunha, Silvio do Desterro
Institución
Resumen
This work presents three operationally simple laboratory protocols for monocrystal growth of small-molecule organic compounds, which have been applied with success in the last ten years for the formation of single crystals for X-ray structural studies. In addition, five structure hints were formulated as general guidelines for selecting a small-molecule organic compound as a candidate for monocrystal growth: molecular weight >200 D, melting point >100 ºC, two or more aromatic rings in the structure, at least two sites for intermolecular hydrogen bond formation, and a halogen or other heavy atom in the structure.