dc.contributor | | |
dc.contributor | http://lattes.cnpq.br/0236878364579936 | |
dc.contributor | | |
dc.contributor | http://lattes.cnpq.br/2204048396738679 | |
dc.contributor | Anselmo, Caroline Wanderley Souto Ferreira | |
dc.contributor | | |
dc.contributor | Caroline Wanderley Souto Ferreira Anselmo | |
dc.contributor | Medeiros, Aldo da Cunha | |
dc.contributor | | |
dc.contributor | http://lattes.cnpq.br/9873289951810864 | |
dc.creator | Ribeiro, Camila Godinho | |
dc.date.accessioned | 2009-07-06 | |
dc.date.accessioned | 2014-12-17T14:13:40Z | |
dc.date.accessioned | 2022-10-06T12:19:04Z | |
dc.date.available | 2009-07-06 | |
dc.date.available | 2014-12-17T14:13:40Z | |
dc.date.available | 2022-10-06T12:19:04Z | |
dc.date.created | 2009-07-06 | |
dc.date.created | 2014-12-17T14:13:40Z | |
dc.date.issued | 2008-08-12 | |
dc.identifier | RIBEIRO, Camila Godinho. Avaliação de efeitos DW extratos de sambucus australis E sambucus nigra na marcação de constituintes sanguineos com tecnécio-99M, na morfologia de Hemácias de ratos wistar, na topologia plasmidial e na ação do cloreto estanoso no DNA Plasmidial. 2008. 48 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal do Rio Grande do Norte, Natal, 2008. | |
dc.identifier | https://repositorio.ufrn.br/jspui/handle/123456789/13234 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3949924 | |
dc.description.abstract | Radiobiocomplexes are used in nuclear medicine to obtain images and to treat diseases. Blood constituents have been used as radiobiocomplexes. Natural or synthetic products
can influence on the labeling of blood constituents with technetium-99m (99mTc), the morphology of red blood cells and on the stannous chloride (SnCl2) action on plasmid
DNA. Sambucus australis and Sambucus nigra are used in popular culture for treating diseases. The aim of this work was to evaluate the effects of the extracts of Sambucus
australis and Sambucus nigra on the labeling of blood constituents with 99mTc, on morphology of red blood cells of Wistar rats, on the topology of plasmids DNA and the
action against the SnCl2 effects on the DNA of plasmids pBSK. On the labeling of blood constituents with 99mTc it was verified that both extracts were capable to decrease
significantly the radioactivity in the cellular compartment and in the insoluble fraction of plasma. Sambucus australis also decreased the labeling of insoluble fraction of blood cells
with 99mTc. Both extracts did not alter the morphology of red blood cells. Moreover, it was verified that Sambucus nigra did not alter the electrophoretic profile of plasmid DNA, but
decreased the effect of SnCl2 on plasmid DNA. These last results sugest a genotoxic effect and a protective action of Sambucus nigra extract against the SnCl2 action on
plasmid DNA. This work was developed with the contribution of several Departments of biomedical area of the Hospital Universitário Pedro Ernesto, of the UERJ, characterizing a
multidisciplinary experimental research | |
dc.publisher | Universidade Federal do Rio Grande do Norte | |
dc.publisher | BR | |
dc.publisher | UFRN | |
dc.publisher | Programa de Pós-Graduação em Ciências da Saúde | |
dc.publisher | Ciências da Saúde | |
dc.rights | Acesso Aberto | |
dc.subject | Constituintes sangüíneos | |
dc.subject | Tecnécio-99m | |
dc.subject | Cloreto estanoso | |
dc.subject | Morfologia | |
dc.subject | DNA plasmidial | |
dc.subject | Sambucus australis | |
dc.subject | Sambucus nigra | |
dc.subject | Blood constituents | |
dc.subject | Technetium-99m | |
dc.subject | Stannous chloride | |
dc.subject | Morphology | |
dc.subject | Plasmid | |
dc.subject | DNA | |
dc.subject | Sambucus australis | |
dc.subject | Sambucus nigra | |
dc.title | Avaliação de efeitos DW extratos de sambucus australis E sambucus nigra na marcação de constituintes sanguineos com tecnécio-99M, na morfologia de Hemácias de ratos wistar, na topologia plasmidial e na ação do cloreto estanoso no DNA Plasmidial | |
dc.type | masterThesis | |