masterThesis
Influência da superfície do titânio nitretado a plasma em diferentes atmosferas na ativação de plaquetas sanguíneas
Fecha
2015-01-09Registro en:
VITORIANO, Jussier de Oliveira. Influência da superfície do titânio nitretado a plasma em diferentes atmosferas na ativação de plaquetas sanguíneas. 2015. 86f. Dissertação (Mestrado em Engenharia Mecânica) - Centro de Tecnologia, Universidade Federal do Rio Grande do Norte, Natal, 2015.
Autor
Vitoriano, Jussier de Oliveira
Resumen
This study aimed to analyze the biological response of titanium surfaces modified by plasma Ar + N2
+ H2. Titanium disks grade II received different surface treatments Ar + N2 + H2 plasma, constituting
seven groups including only polished samples used as standard. Before and after treatment the samples
were evaluated in terms of topography, crystal structure and wettability, using atomic force
microscopy, X-ray diffraction, Raman spectroscopy and testing of the sessile drop, respectively. Rich
plasma (PRP) was applied to the surfaces modified in culture plates. Images obtained by scanning
electron microscopy of the adhered platelets were analyzed to verify the behavior of platelets in the
different experimental conditions. We verified that the adition of H2 on plasma atmosphere resulted in
more rough surfaces, with round tops. These surfaces, in contrast to that surfaces treated with high
concentration of N2, are less propense to platelet aggregation and, consequently, to the formation of
thrombus when applied in biomedical devices.