Artículos de revistas
Sleep in brain development
With the discovery of rapid eye movement (REM) sleep, sleep was no longer considered a homogeneous state of passive rest for the brain. On the contrary, sleep, and especially REM sleep, appeared as an active condition of intense cerebral activity. The fact that we get large amounts of sleep in early life suggested that sleep may play a role in brain maturation. This idea has been investigated for many years through a large number of animal and human studies, but evidence remains fragmented. The hypothesis proposed was that REM sleep would provide an endogenous source of activation, possibly critical for structural maturation of the central nervous system. This proposal led to a series of experiments looking at the role of REM sleep in brain development. In particular, the influence of sleep in developing the visual system has been highlighted. More recently, non-REM (NREM) sleep state has become a major focus of attention. The current data underscore the importance of both REM sleep and NREM sleep states in normal synaptic development and lend support to their functional roles in brain maturation. Both sleep states appear to be important for neuronal development, but the corresponding contribution is likely to be different
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Short-term homeostasis of REM sleep assessed in an intermittent REM sleep deprivation protocol in the rat Ocampo Garcés, Adrián; Vivaldi Véjar, Ennio (2002)An intermittent rapid eye movement (REM) sleep deprivation protocol was applied to determine whether an increase in REM sleep propensity occurs throughout an interval without REM sleep comparable with the spontaneous sleep ...
Usefulness of a clinical questionnaire for diagnosis of respiratory disorders of sleep in children with neuromuscular diseases Brockmann, P. E.; Holmgren, N. L.; Salinas, P.; Prado, F. (2011)Objetivos: Ainalizar la utilidad de un cuestionario clínico para el diagnóstico de los trastornos respiratorios del sueño (TRS) en niños con enfermedades neuromusculares (ENM). Pacientes y Métodos: Se realizó un cuestionario ...
Measures of location and dispersion of sleep state distributions within the circular frame of a 12:12 light: Dark schedule in the rat Vivaldi Véjar, Ennio; Wyneken, Úrsula; Roncagliolo, Manuel; Ocampo,; Zapata, (Associated Professional Sleep Societies,LLC, 1994)Distributions within a 12:12 light:dark schedule of wakefulness (W), active sleep (AS), quiet sleep (QS) and of QS rich in delta (QSD) and in spindle (QSS) activities were evaluated for 52 days from 15 rats. Angular ...