Artigo
Treatment of experimental periodontitis in rats using repeated adjunctive antimicrobial photodynamic therapy
Fecha
2013-01-01Registro en:
Lasers in Medical Science, v. 28, n. 1, p. 143-150, 2013.
0268-8921
1435-604X
10.1007/s10103-012-1099-y
WOS:000313096400021
2-s2.0-84872314410
4068921369233125
9831236034935598
8399870097572073
4774447118127346
Autor
Universidade Estadual Paulista (Unesp)
University Center of the Educational Foundation of Barretos (UNIFEB)
Federal University of Alfenas
Resumen
The aim of this study was to histologically and histometrically evaluate the influence of repeated adjunctive antimicrobial photodynamic therapy (aPDT) on bone loss (BL) in furcation areas in rats. Periodontitis was induced by placing a ligature around the mandibular molar in 75 rats. The animals were divided into five groups: the SS group was treated with saline solution (SS); the SRP group received scaling and root planing (SRP); the aPDT1 group received SRP as well as toluidine blue (TBO) and low-level laser therapy (LLLT; InGaAlP, 660 nm; 4.94 J/cm2/point) postoperatively at 0 h; the aPDT2 group received SRP as well as TBO and LLLT postoperatively at 0, 24, 28, and 72 h; and the aPDT3 group received SRP, TBO, and LLLT postoperatively at 0, 48, 96, and 144 h. The area of BL in the furcation region of the molar was histometrically analyzed. Data were analyzed statistically (P < 0.05). Animals treated with a single episode of aPDT showed less BL at days 7 and 30 than those who received only SRP treatment. No significant differences were found among the aPDT groups (P > 0.05). Repeated aPDT did not improve BL reduction when compared to a single episode of aPDT. © 2012 Springer-Verlag London Ltd.
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