Artigo
Dimensional correlates of poor insight in obsessive-compulsive disorder
Fecha
2011-08-15Registro en:
Progress in Neuro-Psychopharmacology and Biological Psychiatry, v. 35, n. 7, p. 1677-1681, 2011.
0278-5846
1878-4216
10.1016/j.pnpbp.2011.05.012
2-s2.0-79961127104
3837157956819433
Autor
University of Heidelberg
Yale University School of Medicine
Universidade Estadual Paulista (Unesp)
Universidade Federal do Rio de Janeiro (UFRJ)
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)
Universidade de São Paulo (USP)
Resumen
Background: Cross-sectional studies have associated poor insight in patients with obsessive-compulsive disorder (OCD) with increased OCD symptom severity, earlier age of onset, comorbid depression, and treatment response. The goal of this current study was to examine the relationship between dimensions of OCD symptomatology and insight in a large clinical cohort of Brazilian patients with OCD. We hypothesized that poor insight would be associated with total symptom severity as well as with hoarding symptoms severity, specifically. Methods: 824 outpatients underwent a detailed clinical assessment for OCD, including the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS), the Brown Assessment of Beliefs Scale (BABS), a socio-demographic questionnaire, and the Structured Clinical Interview for axis I DSM-IV disorders (SCID-P). Tobit regression models were used to examine the association between level of insight and clinical variables of interest. Results: Increased severity of current and worst-ever hoarding symptoms and higher rate of unemployment were associated with poor insight in OCD after controlling for current OCD severity, age and gender. Poor insight was also correlated with increased severity of current OCD symptoms. Conclusion: Hoarding and overall OCD severity were significantly but weakly associated with level of insight in OCD patients. Further studies should examine insight as a moderator and mediator of treatment response in OCD in both behavioral therapy and pharmacological trials. Behavioral techniques aimed at enhancing insight may be potentially beneficial in OCD, especially among patients with hoarding. © 2011.
Materias
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Obsessive-compulsive disorder: Influence of age at onset on comorbidity patterns
de Mathis, Maria Alice; do Rosario, Maria Conceição; Diniz, Juliana Belo; Torres, Albina Rodrigues; Shavitt, Roseli Gedanki; Ferrão, Ygor Arzeno; Fossaluza, Victor; de Bragança Pereira, Carlos Alberto; Miguel, Eurípedes Constantino -
Obsessive-compulsive disorder: Influence of age at onset on comorbidity patterns
Universidade de São Paulo (USP); Universidade Estadual Paulista (Unesp); Porto Alegre Institute University Center; Obsessive-Compulsive Disorder Brazilian Consortium (C-TOC) (2008-04-01)Purpose: This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset. Methods: Three hundred and thirty OCD patients were consecutively ... -
Obsessive-compulsive disorder: Influence of age at onset on comorbidity patterns
Universidade de São Paulo (USP); Universidade Estadual Paulista (Unesp); Porto Alegre Institute University Center; Obsessive-Compulsive Disorder Brazilian Consortium (C-TOC) (2008-04-01)Purpose: This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset. Methods: Three hundred and thirty OCD patients were consecutively ...