Non-conventional applications of computerized tomography: Analysis of solid dosage forms produced by pharmaceutical industry

dc.contributorUniversidade de Sorocaba - UNISO
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:24:46Z
dc.date.accessioned2022-10-05T18:22:17Z
dc.date.available2014-05-27T11:24:46Z
dc.date.available2022-10-05T18:22:17Z
dc.date.created2014-05-27T11:24:46Z
dc.date.issued2010-08-26
dc.identifierAIP Conference Proceedings, v. 1245, p. 153-159.
dc.identifier0094-243X
dc.identifier1551-7616
dc.identifierhttp://hdl.handle.net/11449/71837
dc.identifier10.1063/1.3448008
dc.identifier2-s2.0-77955792311
dc.identifier2-s2.0-77955792311.pdf
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3920965
dc.description.abstractX-ray computed tomography (CT) refers to the cross-sectional imaging of an object measuring the transmitted radiation at different directions. In this work, we describe a non-conventional application of computerized tomography: visualization and improvements in the understanding of some internal structural features of solid dosage forms. A micro-CT X-ray scanner, with a minimum resolution of 30 μm was used to characterize some pharmaceutical tablets, granules, controlled-release osmotic tablet and liquid-filled soft-gelatin capsules. The analysis presented in this work are essentially qualitative, but quantitative parameters, such as porosity, density distribution, tablets dimensions, etc. could also be obtained using the related CT techniques. © 2010 American Institute of Physics.
dc.languageeng
dc.relationAIP Conference Proceedings
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectComputed Tomography
dc.subjectGranules
dc.subjectSolid Dosage Forms
dc.subjectTablets
dc.subjectX-ray
dc.titleNon-conventional applications of computerized tomography: Analysis of solid dosage forms produced by pharmaceutical industry
dc.typeTrabalho apresentado em evento


Este ítem pertenece a la siguiente institución