COX-2 and TGF-β expression in proliferative disorders of canine prostate

Artigo

Fecha

2010-05-01

Registro en:

Brazilian Journal of Veterinary Pathology, v. 3, n. 1, p. 31-36, 2010.

1983-0246

http://hdl.handle.net/11449/71682

2-s2.0-79952365903

9795829022108105

http://repositorioslatinoamericanos.uchile.cl/handle/2250/3920827

Autor

Universidade Estadual Paulista (Unesp)

Universidade Estadual de Londrina (UEL)

Universidade Federal de Goiás (UFG)

Institución

Universidade Paulista Júlio de Mesquita Filho (Brasil)

Resumen

COX-2 and TGF-β expression was determined in order to correlate non-neoplastic lesions, preneoplastic lesions and carcinoma in the prostate of dogs. The results show that neoplastic and preneoplastic lesions express more COX-2 and TGF-β when compared to carcinomas, which suggests these proteins may cooperate in the process of prostate tumorigenesis.

Materias

Carcinoma prostate

COX-2

Dog

Preneoplastic lesions

Tgf-β .

Canis familiaris

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