Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:21:18Z
dc.date.accessioned2022-10-05T17:56:11Z
dc.date.available2014-05-27T11:21:18Z
dc.date.available2022-10-05T17:56:11Z
dc.date.created2014-05-27T11:21:18Z
dc.date.issued2005-04-01
dc.identifierPharmazie, v. 60, n. 4, p. 263-264, 2005.
dc.identifier0031-7144
dc.identifierhttp://hdl.handle.net/11449/68192
dc.identifierWOS:000228532600005
dc.identifier2-s2.0-17644362688
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3917761
dc.description.abstractA simple, sensitive and accurate spectrophotometric method was developed for the assay of gatifloxacin in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 287 nm for gatifloxacin tablet solutions. The linearity range was found to be 4.0-14.0 μg/mL for gatifloxacin. It was also found that the excipients in the commercial tablets did not interfere with the method.
dc.languageeng
dc.relationPharmazie
dc.relation1.016
dc.relation0,375
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectexcipient
dc.subjectgatifloxacin
dc.subjectquinoline derived antiinfective agent
dc.subjectaccuracy
dc.subjectanalytic method
dc.subjectaqueous solution
dc.subjectcalibration
dc.subjectcorrelation coefficient
dc.subjectdrug determination
dc.subjectlinear regression analysis
dc.subjectreproducibility
dc.subjectstatistical analysis
dc.subjecttablet formulation
dc.subjectultraviolet spectrophotometry
dc.subjectvalidation process
dc.subjectAnti-Infective Agents
dc.subjectCalibration
dc.subjectFluoroquinolones
dc.subjectReference Standards
dc.subjectReproducibility of Results
dc.subjectSpectrophotometry, Ultraviolet
dc.subjectTablets
dc.titleDevelopment and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets
dc.typeArtigo


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