Müller cells and diabetic retinopathy.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], v. 28, n. 9, p. 977-980, 1995.
Universidade Estadual Paulista (Unesp)
Müller cells provide nutrition for neural cells. We studied the structure and ultrastructure of Müller cells in the retina of thirty 3-month old Wistar rats, divided equally into 3 groups: normal rats, alloxan diabetic rats and treated alloxan diabetic rats, 1 and 12 months after induction of diabetes. We observed that the Müller cell nuclei under light microscope examination had hexagonal shape and higher density than the other nuclei. Differences between groups could be observed only by electron microscopy. In the diabetic rats, Müller cells presented dispersion of nuclear chromatin and electrondense nuclear granulations, with the presence of increased glycogen, dense bodies and lysosomes in the cytoplasm. The alterations were more frequent in the perivascular region and at 12 months. The treated diabetic rats exhibited some alterations we observed in diabetic rats, but these alterations were less intense. We conclude that, despite the treatment, the diabetic retinopathy continues to evolve.
Showing items related by title, author, creator and subject.
Diabetic peripheral neuropathy in ambulatory patients with type 2 diabetes in a general hospital in a middle income country: a cross-sectional study Unknown author (Public Library of Science, 2014)AIM: We aimed to estimate the morbidity rate and associated factors for diabetic peripheral neuropathy (DPN) in a low-middle income country setting. METHODS: Cross-sectional study, data was gathered at Peru's Ministry of ...
Alterations in glucose metabolism on cognition: A possible link between diabetes and dementia González-Reyes R.E.; Aliev G.; Ávila-Rodrigues M.; Barreto G.E. (Bentham Science Publishers, 2016)
Antioxidative potential of antidiabetic agents: A possible protective mechanism against vascular complications in diabetic patients Yaribeygi H.; Butler A.E.; Barreto G.E.; Sahebkar A. (Wiley-Liss Inc., 2019)