HIPERTERMIA EM RATOS INDUZIDA PELA LESAO ELETROLITICA DO MESENCEFALO: PARTICIPACAO DAS PROSTAGLANDINAS

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:17:55Z
dc.date.accessioned2022-10-05T17:28:53Z
dc.date.available2014-05-27T11:17:55Z
dc.date.available2022-10-05T17:28:53Z
dc.date.created2014-05-27T11:17:55Z
dc.date.issued1993-12-01
dc.identifierRevista de Ciencias Biomedicas, v. 14, p. 23-32.
dc.identifier0101-322X
dc.identifierhttp://hdl.handle.net/11449/64431
dc.identifier2-s2.0-0027747024
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3914488
dc.description.abstractThe present studies were conducted to determine the role of prostaglandins in the etiology of a rise of body temperature observed in rats after electrolytic lesion made on the dorsal mesencephalic areas. This hyperthermia was abolished by intraperitoneal administration of indomethacin, an inhibitor of prostaglandins synthesis. These results strengthen the suggestion of a similar mechanism for both neurogenic hyperthermia and the fevers produced by pyrogens. However, until further experiments are carried out, the possibility of lesion in producing hyperthermia by different mechanisms cannot be ruled out.
dc.languagespa
dc.relationRevista de Ciencias Biomedicas
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectindomethacin
dc.subjectinduced hyperthermia
dc.subjectmesencephalon
dc.subjectprostaglandins
dc.subjectrats
dc.subjectwounds and injuries
dc.subjectindometacin
dc.subjectprostaglandin derivative
dc.subjectprostaglandin synthesis inhibitor
dc.subjectunclassified drug
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectbrain injury
dc.subjectcontrolled study
dc.subjecthyperthermia
dc.subjectintravenous drug administration
dc.subjectmale
dc.subjectnonhuman
dc.subjectrat
dc.subjectthermoregulation
dc.titleHIPERTERMIA EM RATOS INDUZIDA PELA LESAO ELETROLITICA DO MESENCEFALO: PARTICIPACAO DAS PROSTAGLANDINAS
dc.typeArtigo


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