Natriuresis induced by cholinergic stimulation of the locus coeruleus in the rat

dc.contributorUniversidade de São Paulo (USP)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T08:18:43Z
dc.date.accessioned2022-10-05T17:25:15Z
dc.date.available2014-05-27T08:18:43Z
dc.date.available2022-10-05T17:25:15Z
dc.date.created2014-05-27T08:18:43Z
dc.date.issued1990-04-01
dc.identifierPhysiology and Behavior, v. 47, n. 4, p. 605-610, 1990.
dc.identifier0031-9384
dc.identifierhttp://hdl.handle.net/11449/63974
dc.identifier10.1016/0031-9384(90)90065-C
dc.identifierWOS:A1990DA76300001
dc.identifier2-s2.0-0025248593
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3914123
dc.description.abstractCarbachol injected into the locus coeruleus (LC) induced a dose-dependent natriuresis in the rat. This natriuresis was maintained above control levels during the 120 min of urine sampling. Seizures and arterial blood pressure increase were also observed but they disappeared within 20 min after carbachol injection. Natriuresis was not obtained with either injections of carbachol outside the LC or with hypertonic solutions injected into the LC. Injection of atropine into the LC blocked the natriuresis induced by carbachol. In summary, our data show that carbachol induces natriuresis by an action on muscarinic receptors located in the LC region. © 1990.
dc.languageeng
dc.relationPhysiology and Behavior
dc.relation2.517
dc.relation1,088
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectBlood pressure
dc.subjectCarbachol
dc.subjectCholinergic stimulation
dc.subjectLocus coeruleus
dc.subjectNatriuresis
dc.subjectSeizures
dc.subjectatropine
dc.subjectcarbachol
dc.subjectmuscarinic receptor
dc.subjectanimal cell
dc.subjectanimal experiment
dc.subjectblood pressure
dc.subjectintracerebral drug administration
dc.subjectlocus ceruleus
dc.subjectmale
dc.subjectnatriuresis
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectrat
dc.subjectAnimal
dc.subjectBlood Pressure
dc.subjectBrain Mapping
dc.subjectCholinergic Fibers
dc.subjectLocus Coeruleus
dc.subjectMale
dc.subjectNeurons
dc.subjectPotassium
dc.subjectRats
dc.subjectRats, Inbred Strains
dc.subjectReceptors, Cholinergic
dc.subjectSupport, Non-U.S. Gov't
dc.subjectWater-Electrolyte Balance
dc.titleNatriuresis induced by cholinergic stimulation of the locus coeruleus in the rat
dc.typeArtigo


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